Injuries: Tyrann Mathieu cracks thumb; DJax injures fibulaZach Mettenberger's Sunday has been cut short by J.J. Watt.
The Tennessee Titans quarterback suffered a right shoulder injury after being driven into the turf by the Houston Texans star. Mettenberger remained on the field for several minutes before walking slowly to the sideline. He was eventually escorted to the locker room, never returning to the contest.
Jake Locker replaced Mettenberger and threw an interception on his first pass attempt.
Mettenberger had released his pass -- a 7-yard completion to Kendall Wright -- before Watt drove the rookie into the turf. Watt was not flagged for the hit, though he certainly could have been.
Watt and Mettenberger have some history. After Mettenberger's first career start last month, Watt criticized the quarterback for his social media presence in the days after being named Tennessee's starter.
"I take this game seriously," Watt said at the time. "If I were a rookie being named a starter for the first time, I'd be a little more focused."
In addition, guard Chance Warmack hurt his ankle, also staying out of the game.
What other game-day injuries are we following?
1. Redskins wideout DeSean Jackson was carted off with a fibula contusion and was ruled out after initially being called questionable. He later returned to the sideline.
2. The Broncos will take on the Chiefs without Julius Thomas and Aqib Talib, both of whom are inactive.
3. Bills defensive end Marcell Dareus went to the locker room with a groin injury and stayed out of the game.
4. Cardinals safety Tyrann Mathieu suffered a cracked thumb, while running back Andre Ellington has a hip pointer and guard Paul Fanaika has a high ankle sprain.
5. Colts cornerback Vontae Davis was ruled out with a concussion.
6. Giants running back Rashad Jennings exited the game with an ankle injury and never returned.
7. Texans CB Johnathan Joseph suffered an Achilles injury in the win over Tennessee and didn't return.
8. Giants offensive lineman Geoff Schwartz was carted off with an ankle injury and was ruled out.
9. Vikings rookie Anthony Barr left the game with a knee injury and didn't return.
10. Steelers defensive lineman Brett Keisel was ruled out with a left triceps injury. NFL Media Insider Ian Rapoport reported Sunday night that team believes the triceps is torn, which would end his season, per two sources informed of the injury. He'll have an MRI to confirm.
11. Browns receiver Miles Austin was taken to the hospital after experiencing abdominal pain, according to WKNR-AM.
12. The Titans confirmed to The Tennesseean that receiver Justin Hunter will remain hospitalized overnight after suffering a lacerated spleen.